There are two ways to reach lonavala from pune. One is through the countryside route crossing Pirangut, Gothawade, Kolvan, Pawananagar and then along beautiful Pawna lake to Lonavala. The route if full of twists and turns so if you are a pro in then go for it. The route is really nice and adventurous.
Stay safe as there are few places which are accident prone like Nigdi to Dehuroad (single way) ,Vadgoan Phata , karla Phata , Manashakti (Valvan)
Some precautions to take incase you travel by cycle or motorcycle is, do not enter the lanes of Pune-Mumbai expressway where two-wheeler are not allowed. Make note that there are lots of unfortunate incidents happening every day on this route, so keep the left most lane to enjoy a hastle-free ride!